1. The cell: basic life unit
a) Prokaryotic and eukaryotic cells
b) Methods in cell biology
c) Cellular organization: Information processing organelles; The endomembrane system; Energy processing organlles; Cell shape and movement; Cell surfaces and junctions.
d) Basic principles of stem cell technology and regenerative medicine.
2. Cell communication and homeostasis
a) Cell communication
b) Cellular receptors
c) Second messengers
d) Regulation by hormones
e) Cell homeostasis
f) The cell cycle
3. Information pathways and inheritance
a) The molecular basis of inheritance: genes and chromosomes
b) The organization of eukaryotic genomes; the human genome; the structure of DNA
c) DNA replication and repair
d) From gene to protein
e) Transcriptional and post-transcriptional regulation of gene expression
f) DNA technology: DNA cloning and sequencing; genomics; genetically-modified models.
Bibliography of reference
David Sadava, H. Craig Heller, Gordon H. Orians, and William K. Purves (2009). Life-The Science of Biology, W.H. Freeman and Company. (9ª Edição)
Campbell, N & Reece, J. (2009) Biology, Pearson Education (8ª Edição)
Clark, DP & Pazdernik, NJ (2012) Molecular Biology, Academic Cell Press (2ª Edição).
Azevedo C & Sunkel C (2012) Biologia Celular e Molecular, Lidel.
Alberts et al. (2008), Molecular Biology of the Cell, Garland Science(5ª Edição)