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Introduction to Nuclear Chemistry and Radiopharmacy
EB 2018 . 2019 - 2º semestre
syllabus and bibliography Introduction to Nuclear Chemistry. Radionuclides' prodcution. Nuclear Medicine. Detection and quantification techniques. Particle accelerators.
Introduction to Radiopharmacology and its history. Radiopharmacology equipment and laboratory. Radiopharmaceuticals' characteristics. Basic methods of radioactive marking. Design and industrial production of radiopharmaceuticals. Quality control. Storage and management of residues and waste. Brief introduction to practical radio pharmacology. Brief review of radiopharmaceutcial localisation mechanisms. Radionuclides in pharmacology: pharmacokinetics and and pharmacodynamics. Biodistribution. Binding assays. Introduction to the use of radiotracers/radiopharmaceuticals in Nuclear Medicine. Introductio to auto-radiography. Radionuclides' applications in Space Biology and Medicine. Radiopharmacology laws, regulations and practice. Bibliography of reference Bushberg JT, Seibert JA, Leidnoldt EM, Boone JM The essential physics of medical imaging, Lippincott Williams & Wilkins, NY (2nd ed.)
Hendee WR & Ritenou ER Medical imaging physics, Wiley-Liss, NY (4th ed., 2002) Gopal B Saha Fundamentals of Nuclear Pharmacy, Springer, NY (5th ed. 2004). Leslie WD & Greenberg ID Nuclear medicine, Landes Bioscience, Georgetown (2003). Pandit NK Introduction to the pharmaceutical sciences, Lippincott Williams & Wilkins, NY (2006). Sampson CE Textbook of radiopharmacy theory and practice, Gordon and Breach Science Publishers, NY (3rd ed., 1999). Tubis M & Wolf W Radiopharmacy, Wiley Interscience, NY (1976). Tpzer TN & Rowland M - Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy, Lippincott Williams & Wilkins, NY (2006). Farmacopeia BP, EP, USP;
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