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Elements of Biophysics
F+B 2019 . 2020 - 1º semestre
syllabus and bibliography Introduction to bioelectrical phenomena. Structure and function of the nerve cell. Diffusion and transport through membranes. Resting membrane potential. Electrical properties of excitable membrane. Functional properties of dendrites. Action potential and model of Hodgkin - Huxley. Currents and gating mechanisms. Diversity on gated ion channels. Molecular structure and single-channel currents. Synaptic transmission: pre- and postsynaptic mechanisms. Synaptic plasticity.
Bibliography of reference JOHNSTON, Daniel;WU,Samuel M.-S.- Foundations of Cellular Neurophysiology
Cambridge, Massachusetts,The MIT Press,1995,676 p.ISBN 0-262-10053-3 HILLE,Bertil-Ionic Channels of Excitable Membranes, 3ª ed. Sinauer Associates, Inc., Massachusetts, 2001, 841 p.ISBN 0-87893-321-2 FAIN,Gordon L.-Molecular and Cellular Physiology of Neurons, Cambridge, Massachusetts, Harvard University Press,1999,693 p.ISBN 0-674-58155-5 HOPPE, Walter; LOHMANN, Wolfgang; MARKL, Hubert, ZIEGLER, Hubert, Eds. Biophysics. Berlin, Springer-Verlag,1983, 941 p.ISBN 3-540-12083-1
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